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Enobosarm Wikipedia Enobosarm Enobosarm (also known as Ostarine, GTx‑024, STX‑209) is a selective androgen receptor modulator (SARM) that has been investigated for the treatment of conditions such as muscle wasting, osteoporosis, and sarcopenia. It functions by binding to the androgen receptor with high affinity but without the full spectrum of anabolic activity seen in traditional testosterone analogues, thereby aiming to provide skeletal‑muscle benefits while minimizing adverse effects on the prostate, skin, and other tissues. --- Mechanism of Action Androgen Receptor Binding: Enobosarm binds competitively to the androgen receptor (AR) with an affinity similar to that of endogenous dihydrotestosterone (DHT). Selective Gene Activation: Once bound, it forms a ligand‑receptor complex that translocates into the nucleus and selectively modulates transcription of AR‑responsive genes. Tissue Selectivity: The compound exhibits preferential activity in skele |
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